"I want to be boring. I would like people like me, in the future, to not be shocking. I want to be good at what I do, but I just want people to look and think, OK. When a man wears a dress it shouldn't be shocking; you shouldn't look twice unless you're thinking, Nice dress!"
Consistency and discipline over motivation. Most psychological skills get easier as I get older, but motivation remains as hard as ever. This guy argues that, instead of trying or waiting to feel motivated, it's better to just devote blocks of time where you force yourself to do stuff you don't feel like doing, and this is easier if you start each session with mental planning.
This is definitely the right way to do your taxes, but if we're talking about creative work, I think it should be considered in balance with the opposite position: that if your vision isn't lighting a fire under your ass, you need to reach deeper inside yourself until you find one that does.
CRISPR is indeed revolutionary in that it enables rapid and efficient genetic manipulation in a wide range of species. However, the notion that CRISPR will result in escape of GMOs from labs is a completely separate question.
Their example, the fruit fly, can itself provide evidence to the contrary. Because of how easy genetic manipulation is in the fruit fly, nearly every gene has already been deleted, and all known markers and tools inserted, in labs for decades all over the globe. Yet despite their small size and wings to fly out of labs, the world is not yet overrun by GM fruit flies.
The reason is simple: evolution gives wild fruit flies the greatest advantage, with an elegant and robust unmodified genome selected over millions of years to function in the world. Nearly all genetic manipulations confer disadvantages that are out-competed by wild flies.
New subject: this excellent reddit comment explains why whole milk is better than lowfat milk, including a calorie to lactose ratio that enables most lactose intolerant people to consume whole milk in moderation.
]]>In a paper published yesterday, Valentino Gantz and Ethan Bier, both at the University of California, San Diego, demonstrated the first successful implementation of a CRISPR-Cas9-based gene drive in the germ line of fruit flies. The CRISPR gene drive is a powerful piece of technology that all but guarantees an engineered trait is passed on to every single offspring. Within months or years, it has the ability to alter an entire population of a sexually reproducing species.
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Modified critters could easily escape, or carefully designed species released into the wild could have unintended consequences, sparking a cascade of ecological changes that may be all but impossible to reverse.
Next, Assembly line nuclear reactors are quietly building steam in the northwest. I actually think this is good. My big objection to nuclear power is political: where the energy flows from the center out, the political power flows from the center out, and the bigger the plant, the bigger the control system. But smaller reactors could be run by towns or neighborhoods in which you're more likely to have a voice, and they could stay autonomous and energy-rich as dysfunctional big systems break down.
Back to scary: What cockroaches with backpacks can do. Mostly it's about surveillance, and I wonder if cockroach cyborgs are a better fit with democratic, distributed surveillance, where anyone can watch anyone, or centralized surveillance where powerful institutions can lock their power in place.
And the other day on the subreddit, yiedyie made a post called The Point of No-Return, "the point at which all daredevils and tricksters instead of jumping over cliffs in squirrel flying suits, making cults, or make cyber-scams, etc, start instead messing with the system."